The medical uses of CBD are numerous. A huge range of people is making use of it these days to get a relief from a particular medical condition. Taking this into consideration, we have elaborated how CBD works inside your body in order to let you make an informed decision.
If you would like to be one of such people, then in the right spot. However, before you choose to make use of CBD for any given medical condition, it is of prime importance to make sure that you are familiar with the mode of action of CBD.
Active Compound Cannabidiol
The active compound in hemp is commonly referred to as cannabidiol or CBD which is unique in a sense that unlike THC, it is not psychoactive in nature and hence enables you to avoid getting high. This difference is primarily due to THC acting directly to the CB1 and CB2 receptors in order to stimulate them while CBD holds a rather indirect action on the receptors.
A few of the common sensations which are under the control of cannabinoid receptors include appetite, mood, pain sensation, and memory.
These receptors which are primarily divided into two major categories termed as CB1 and CB2 can either be stimulated by the endocannabinoids which are naturally produced by the brain inside the human body, or they can be stimulated with the use of exocannabinoids such as those which are produced by plants, for example, hemp.
CB1 & CB2 Receptors
While the CB2 receptors are a major feature of the immune system, CB1 receptors are commonly found in the central nervous system and a small proportion may also be a part of the kidneys, lungs, or liver.
A few of the common functions plays by CB1 receptor include the release of neurotransmitters or cannabis products which are known to produce the psychoactive effect, maintenance of the body’s homeostasis via taking part in lipogenesis occurring inside the liver, and sensations like pleasure, memory, appetite, concentration, and pain tolerance.
On the other hand, CB2 receptors are primarily involved in controlling the prominent features of the immune system such as apoptosis or immune suppression. It has been established that CB2 plays an indispensable role in modulating the pain sensation. CB2 is also known to play a crucial role in a whole range of diseases from liver and kidney problems to neurodegenerative disorders.
CBD & THC
The mode of action of CBD is remarkably different as compared to THC since it is not involved in direct stimulation of the aforementioned receptors. The primary impact of CBD is caused on other receptors such as Serotonin, Adenosine, and vanilloid.
For instance, the stimulation of TRPV-1 receptor by CBD mediates a variety of processes including inflammation, body temperature, and pain perception. Moreover, CBD is known to cause an inhibition in the functioning of FAAH enzyme that directly acts on the CB1 receptor and enables THC to produce its psychoactive effect.
Anti-anxiety & Anti-Inflammatory
The anti-anxiety or anti-inflammatory impact of the CBD is mainly associated with the activation of adenosine receptor. Stimulation of adenosine promotes the release of dopamine and glutamate neurotransmitters.
While processes like motor control, cognition, motivation, and reward mechanism is associated with the release of dopamine, glutamate is involved in learning, memory formation, excitatory signals, and cognition.
CBD & Serotonin
CBD Consumption & Impact